Detalhe da pesquisa
1.
Polygenic architecture of rare coding variation across 394,783 exomes.
Nature
; 614(7948): 492-499, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36755099
2.
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
Nature
; 595(7865): 107-113, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33915569
3.
Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis.
Genome Res
; 30(4): 611-621, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32312741
4.
Dispersal syndromes drive the formation of biogeographical regions, illustrated by the case of Wallace's Line.
Glob Ecol Biogeogr
; 30(3): 685-696, 2021 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-33776580
5.
Inference and visualization of DNA damage patterns using a grade of membership model.
Bioinformatics
; 35(8): 1292-1298, 2019 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30192911
6.
Visualizing the structure of RNA-seq expression data using grade of membership models.
PLoS Genet
; 13(3): e1006599, 2017 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-28333934
7.
Correction: Visualizing the structure of RNA-seq expression data using grade of membership models.
PLoS Genet
; 13(5): e1006759, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28549067
8.
A new sequence logo plot to highlight enrichment and depletion.
BMC Bioinformatics
; 19(1): 473, 2018 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30526486
9.
Single-cell multi-ome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis.
Nat Genet
; 56(4): 627-636, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38514783
10.
Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types.
Nat Commun
; 15(1): 563, 2024 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38233398
11.
CRISPR Screening Uncovers a Long-Range Enhancer for ONECUT1 in Pancreatic Differentiation and Links a Diabetes Risk Variant.
bioRxiv
; 2024 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38746154
12.
Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.
Nat Genet
; 56(4): 615-626, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38594305
13.
Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq.
bioRxiv
; 2023 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36747789
14.
An encyclopedia of enhancer-gene regulatory interactions in the human genome.
bioRxiv
; 2023 Nov 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38014075
15.
SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease.
Cell Genom
; 2(7)2022 Jul 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35873673
16.
SAIGE-GENE+ improves the efficiency and accuracy of set-based rare variant association tests.
Nat Genet
; 54(10): 1466-1469, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36138231
17.
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.
Nat Genet
; 54(10): 1572-1580, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36050550
18.
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity.
Nat Genet
; 54(6): 827-836, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35668300
19.
Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics.
Nat Genet
; 54(10): 1479-1492, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36175791
20.
Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics.
bioRxiv
; 2021 Nov 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34845454